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Real-Coded Genetic Algorithm to Reveal Biological Significant Sites of Remotely Homologous Proteins
Sung-Joon Park and Masayuki Yamamura
Interdisciplinary Graduate School of Science and Engineering
Tokyo Institute of Technology
R1-418, 4259 Nagatsuta, Midori
Yokohama, 226-8502, Japan
{park,my}@es.dis.titech.ac.jp
http://www.es.dis.titech.ac.jp/
Abstract. Discovering biological importance from protein structures needs to utilize heuristic approaches. Since three-dimensional (3D) protein structures play a crucial role in biological reactions, comparing new proteins with well-studied proteins is vital for understanding the native functions. A few residues forming in geometrically close positions activate such biological functions.
LNCS 2724, p. 1602 ff.
lncs@springer.de
© Springer-Verlag Berlin Heidelberg 2003